Carboplatin 150/450mg
Carboplatin is used to treat a number of Cancers which include ovarian cancer, lung cancer, head and neck cancer, brain cancer, and neuroblastoma, testicular cancer and triple-negative breast cancer.
Common side effects of carboplatin include:
nausea, vomiting, numbness and tingling of extremities, ear infection, pain, weakness, allergic reactions, and hair loss.
Serious side effects of carboplatin include: bleeding and reduced blood cells, including reduced red blood cells (anemia) and platelets (needed for proper blood clotting);
unusual bruising or bleeding, black tarry stools or blood in the urine;
infection;
life-threatening allergic reaction;
kidney and liver problems; or
loss of hearing or ringing in the ears.
Cisplatin 50mg
Cisplatin is used for the treatment of advanced ovarian cancer, testicular cancer, and bladder carcinoma
Nausea, Vomiting, Diarrhea, Temporary hair loss, Loss in ability to taste food, Hiccups, Dry mouth, Dark urine, Decreased sweating, Dry skin , Signs of dehydration, Rash, Itching, Blurred vision, Dizziness, Drowsiness, Headache, Allergic reactions, Blisters, Redness of skin, Peeling of the skin, Restlessness, Lightheadedness, Feeling exhausted too early, Stomach pain, Abdominal pain, Body pain, Swollen legs, Face swelling, Swollen throat, Numbness, Reduce in the number of white blood cells, Bruising and leeding, Anaemia (low number of red blood cells), Feeling sick, Loss of appetite, hearing loss.
Doxorubicin 10/50mg
Doxorubicin is commonly used to treat some leukemias and Hodgkin’s lymphoma, as well as cancers of the bladder, breast, stomach, lung, ovaries, thyroid, soft tissue sarcoma, multiple myeloma.
Cough or hoarseness accompanied by fever or chills
darkening or redness of the skin (if you recently had radiation treatment)
fast or irregular heartbeat
fever or chills
joint pain
lower back or side pain accompanied by fever or chills
pain at the injection site
painful or difficult urination accompanied by fever or chills
red streaks along the injected vein
shortness of breath
stomach pain
swelling of the feet and lower legs
Rare
Black, tarry stools
blood in the urine
pinpoint red spots on the skin
unusual bleeding or bruising.
Gemcitabine 200mg/ 1gm
Pancreatic Cancer, Non-small Cell Lung Cancer,
Breast Cancer,
Ovarian Cancer
Anemia (65%), Elev LFTs (68%), Neutropenia (63%), Leukopenia (62%), Pain (48%), Proteinuria (45%), Fever (41%), Hematuria (35%), Rash (30%), Thrombocytopenia (24%), Dyspnea (23%), Constipation (23%), Diarrhea (19%), Flu-like syndrome (19%), Hemorrhage (17%), BUN increased (16%), Infection (16%), Alopecia (15%), Edema (13%), Elev bilirubin (13%), 1-10%, Paresthesia (2-10%), Creatinine increased (2-8%), Inj site reactions (4%), Bronchospasm (2%)
Postmarketing Reports
Cardiovascular: CHF, MI, arrhythmias, supraventricular arrhythmias
Vascular disorders: Peripheral vasculitis, gangrene, capillary leak syndrome
Skin: Cellulitis, pseudocellulitis, severe skin reactions, including desquamation and bullous skin eruptions
Hepatic: Hepatic failure, hepatic veno-occlusive disease
Pulmonary: Interstitial pneumonitis, pulmonary fibrosis, pulmonary edema, ARDS
Pulmonary: Pulmonary eosinophilia
Blood and lymphatic system: Thrombotic microangiopathy
Oxaliplatin 50/100mg
For management of Colorectal Cancers
Peripheral neuropathy (76%), Anemia (64%), Nausea (64%), Fatigue (61%), Diarrhea (46%), Vomiting (37%), Abdominal pain (31%), Constipation(31%), Thrombocytopenia (30%), Fever (25%), Anorexia (20%), Leukopenia (13%), Dyspnea (13%), Cough (11%), 1-10%, Edema (10%), Neutropenia (7%), Pharyngolaryngeal dysesthesia (1-2%), <1%, Pulmonary fibrosis, Posterior leukoencephalopathy syndrome.
Paclitaxel 30/100/260mg
Novapressin contains
Breast cancer, Ovarian cancer, Non-Small cell Lung cancer, AIDS related Kaposi’s Sarcoma
Novapressin is indicated in the treatment of bleeding oesophageal varices and emergency treatment of type 1 hepatorenal syndrome,as defined by IAC (International Ascites Club) criteria.
Neutropenia (78-100%), Alopecia (55-96%), Anemia (47-96%), Arthralgia/myalgia (93%), Diarrhea (90%), Leukopenia (90%), Nausea/vomiting (9-88%), Opportunistic infections (76%), Peripheral neuropathy (42-79%), Thrombocytopenia (4-68%), Mucositis (5-45%), Hypersensitivity (2-45%), Renal impairment (34%), Hypotension (17%), 1-10%, Bradycardia (3%), <1%, Grand mal seizures, Cardiac conduction abnormalities.
paleness of face and body and a slight blood pressure increase, headache and, local necrosis, abdominal pain, nausea, diarrhoea and spontaneous evacuation. Dyspnea, hyponatraemia and hypokalaemia
Docetaxel 20/80mg
Breast Cancer, Prostate cancer, Non-Small cell Lung cancer
>50% Alopecia, Anemia, Leukopenia, Neutropenia, Asthenia, 10-50%, Fever, Infections, Fluid retention, Hypersensitivity, Skin reactions, Diarrhea, Nausea, Vomiting, Sensory neuropathy, Myalgia, Nail changes, 1-10%, Arthralgia, Thrombocytopenia.
Doxorubicin 50mg
Doxorubicin is commonly used to treat some leukemias and Hodgkin’s lymphoma, as well as cancers of the bladder, breast, stomach, lung, ovaries, thyroid, soft tissue sarcoma, multiple myeloma.
Cough or hoarseness accompanied by fever or chills
darkening or redness of the skin (if you recently had radiation treatment)
fast or irregular heartbeat
fever or chills
joint pain
lower back or side pain accompanied by fever or chills
pain at the injection site
painful or difficult urination accompanied by fever or chills
red streaks along the injected vein
shortness of breath
stomach pain
swelling of the feet and lower legs
Rare
Black, tarry stools
blood in the urine
pinpoint red spots on the skin
unusual bleeding or bruising.
Gemcitabine 200mg/ 1gm
Pancreatic Cancer, Non-small Cell Lung Cancer,
Breast Cancer,
Ovarian Cancer
Anemia (65%), Elev LFTs (68%), Neutropenia (63%), Leukopenia (62%), Pain (48%), Proteinuria (45%), Fever (41%), Hematuria (35%), Rash (30%), Thrombocytopenia (24%), Dyspnea (23%), Constipation (23%), Diarrhea (19%), Flu-like syndrome (19%), Hemorrhage (17%), BUN increased (16%), Infection (16%), Alopecia (15%), Edema (13%), Elev bilirubin (13%), 1-10%, Paresthesia (2-10%), Creatinine increased (2-8%), Inj site reactions (4%), Bronchospasm (2%)
Postmarketing Reports
Cardiovascular: CHF, MI, arrhythmias, supraventricular arrhythmias
Vascular disorders: Peripheral vasculitis, gangrene, capillary leak syndrome
Skin: Cellulitis, pseudocellulitis, severe skin reactions, including desquamation and bullous skin eruptions
Hepatic: Hepatic failure, hepatic veno-occlusive disease
Pulmonary: Interstitial pneumonitis, pulmonary fibrosis, pulmonary edema, ARDS
Pulmonary: Pulmonary eosinophilia
Blood and lymphatic system: Thrombotic microangiopathy.
PVC free IV set for administration of drugs which can react with PVC in normal IV sets (eg: Paclitaxel, Docetaxel etc)
Temozopamide 20/100mg. Capsule
Astrocytoma, Glioblastoma Multiforme
Alopecia (55-69%), Lymphopenia (55%), Nausea (53%), Vomiting (42%), Headache (41%), Fatigue (34%), Constipation (33%), Anorexia (9-27%), Convulsions (23%), Thrombocytopenia (19%), Rash (8-19%), Hemiparesis (18%), Diarrhea (16%), Neutropenia (14%), Fever (13%), Asthenia (13%), Dizziness (12%), Peripheral edema (11%), Viral infections (11%), 1-10% (selected), Amnesia (10%), Insomnia (10%), Abdominal pain (5-9%), Ataxia (8%), Back pain (8%), Paresis (8%), URI (8%), Urinary incontinence (8%), UTI (8%), Abnormal vision (5-8%), Pruritus (5-8%), Breast pain (6%), Depression (6%), Confusion (5%), Myalgia (5%), Weight gain (5%), Anemia (4%), Erythema (1%).
Bortezomib 3.5mg
Mantle cell Lymphoma, Multiple myeloma
Asthenia (61-65%), Nausea (61-65%), Diarrhea (51-55%), Anorexia (41-45%), Constipation (41-45%), Thrombocytopenia (41-45%), Peripheral neuropathy (IV: 16-41%; SC: 6-24%), Pyrexia (36-40%), Vomiting (36-40%), Anemia (31-35%), Arthralgia (26-30%), Headache (26-30%), Insomnia (26-30%), Limb pain (26-30%), Dizziness (21-25%), Dyspnea (21-25%), Edema (21-25%), Neutropenia (21-25%), Paresthesia (21-25%), Rash (21-25%), Cough (15-20%), Dehydration (15-20%), URI (15-20%), Rigors, grade 4 toxicity (10-15%), Frequency Not Defined, Hypotension, Anxiety, Pain, Pruritus, Abdominal pain, Dyspepsia, Back pain, Bone pain, Myalgia, Muscle spasms, Herpes zoster, Pneumonia, Blurred vision.
Letrozole 2.5mg tablets
Breast Cancer in Postmenopausal women, Hornone receptor Positive Breast Cancer
Diaphoresis (24%), Bone pain (22%), Hot flashes (19%), Back pain (18%), Dyspnea (18%), Nausea (17%), Night sweats (14%), Cough (13%), Fatigue (13%), 1-10%, Constipation (10%), Hypertension (8%), Chest pain (8%), Diarrhea (8%), Decr wt (7%), Edema (7%), Breast pain (7%), Bone fractures (6%), UTI (6%), Hypercalcemia (5%), Headache (4%), Weakness (4%), Vomiting (3%), Osteoporosis (2%).
Novapressin contains
Terlipressin Acetate (triglycyl¬lysine-vasopressin) 1mg
Novapressin is indicated in the treatment of bleeding oesophageal varices and emergency treatment of type 1 hepatorenal syndrome,as defined by IAC (International Ascites Club) criteria.
paleness of face and body and a slight blood pressure increase, headache and, local necrosis, abdominal pain, nausea, diarrhoea and spontaneous evacuation. Dyspnea, hyponatraemia and hypokalaemia